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deskgameThe Bills have only beaten one team with a winning record this season, so they will want to make a major statement. Let’s get into my best Chiefs vs. Bills predictions and best bets for one of the biggest games of the NFL season to date. deskgamePlaying it safe, if you assume the Eagles will lose to Baltimore as an underdog, they can lose one game in which they are favored and still reach 13 regular season wins. That’s a good wager, and we will lock it in with -115 odds at bet365 Sportsbook. deskgameUnlike Baltimore, Pittsburgh has one of the NFL’s top defenses. The Steelers surrender the second-fewest points and have been strong against the run. Containing Jackson and Henry is a key ingredient in a Steelers victory. deskgameNotre Dame quarterback Riley Leonard is the straw that stirs the drink for the Fighting Irish.